I've only found a few "interactive" clues in the picture...
- Hovering over the backwards "PLAY" replaces the picture with the word "DEAD."
- Hovering over Sara's picture causes her head to turn.
- Hovering over Grissom's head causes him to turn to look at the body, and causes a crack in the window in the door in the back to vanish. It looks like he has a piece of paper in his left pocket.
- Hovering over one of the casinos in the background causes that casino to vanish.
(Sorry, I needed a brief break from tracking down bug repros...)